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Olanzapine For Alzheimer's Disease


   Olanzapine is a drug normally used to treat psychosis,in particular,schizophrenia. It was approved by the FDA in 1996 and is marketed under the trade name Zyprexa,manufactured by Eli Lilly. The drug is now being used to treat alzheimer patients. The normal dose is 5 milligrams daily when used to control psychotic symptoms in alzheimer patients [139]. One recent study reports that 5 to 10 milligrams olanzapine daily effectively reduces aggression, hallucinations, and delusions in alzheimer patients. The most common side effects are a tendency to sleep more and a disturbed gait. Olanzapine does not alter cognition or produce extrapyramidal effects [140].